Health / Pharmaceuticals
1,449 RESULTS WITHIN anywhere FROM https:, India
45-1 Ramsey Road, Shirley, New York 11967, USA, Shirley
Profacgen takes advantage of the most state-of-the-art VS techniques and software tools for hit and lead identification. The application of VS follows a typical sequence of processes with a cascade of sequential filters able to narrow down and choose a set of lead-like hits with potential biological activity. We offer both ligand-based virtual screening (LBVS) and structure-based virtual screening (SBVS) services.... read more
Profacgen takes advantage of the most state-of-the-art VS techniques and software tools for hit and lead identification. The application of VS follows a typical sequence of processes with a cascade of sequential filters able to narrow down and choose a set of lead-like hits with potential biological activity. We offer both ligand-based virtual screening (LBVS) and structure-based virtual screening (SBVS) services.... read more
45-1 Ramsey Road, Shirley, New York 11967, USA, Shirley
Molecular dynamics (MD) simulation is a computer simulation technique that allows one to predict the time dependent evolution of a system of interacting particles using laws of physics. Studying the dynamic development of a biological system with the consideration of protein flexibility is of vital importance since many biological phenomena involving proteins are very dynamic processes which include transport molecular recognition enzyme catalysis and allosteric regulation. The static models produced by NMR X-ray crystallography and homology modeling offer valuable insights into macromolecular structure while MD simulation can provide atomic-level information about protein conformational changes and binding thermodynamics under predefined physiological... read more
Molecular dynamics (MD) simulation is a computer simulation technique that allows one to predict the time dependent evolution of a system of interacting particles using laws of physics. Studying the dynamic development of a biological system with the consideration of protein flexibility is of vital importance since many biological phenomena involving proteins are very dynamic processes which include transport molecular recognition enzyme catalysis and allosteric regulation. The static models produced by NMR X-ray crystallography and homology modeling offer valuable insights into macromolecular structure while MD simulation can provide atomic-level information about protein conformational changes and binding thermodynamics under predefined physiological... read more
45-1 Ramsey Road, Shirley, New York 11967, USA, Shirley
Creative BioMart performs a number of routine protein analyses throughout all project stages to understand the heterogeneity impurity profile and potency of a recombinant protein destined for pharmaceutical use. We have developed the platforms and analytical methods to pursue a comprehensive chemical physical and conformational characterization.... read more
Creative BioMart performs a number of routine protein analyses throughout all project stages to understand the heterogeneity impurity profile and potency of a recombinant protein destined for pharmaceutical use. We have developed the platforms and analytical methods to pursue a comprehensive chemical physical and conformational characterization.... read more
45-1 Ramsey Road, Shirley, New York 11967, USA, Shirley
Creative BioMart is committed to providing advanced tools for protein expression and purification. As a leading supplier for reagents in the biotechnology field we understand the importance of convenient and easy-to-use systems for high level expression and sample purification. We invite you to review our growing range of expression systems resulting from our experience in cloning overexpression and purification.... read more
Creative BioMart is committed to providing advanced tools for protein expression and purification. As a leading supplier for reagents in the biotechnology field we understand the importance of convenient and easy-to-use systems for high level expression and sample purification. We invite you to review our growing range of expression systems resulting from our experience in cloning overexpression and purification.... read more
45-1 Ramsey Road, Shirley, New York 11967, USA, Shirley
Creative BioMart provides service to remove endotoxins (lipopolysaccharides /LPS) from aqueous solutions of a wide range of samples such as proteins antibodies vaccines nucleic acids buffers and cell extracts with excellent sample recovery rate.... read more
Creative BioMart provides service to remove endotoxins (lipopolysaccharides /LPS) from aqueous solutions of a wide range of samples such as proteins antibodies vaccines nucleic acids buffers and cell extracts with excellent sample recovery rate.... read more
45-1 Ramsey Road, Shirley, New York 11967, USA, Shirley
Recombinant proteins expressed in bacteria often form inclusion bodies especially when they are expressed at high levels. Creative BioMart retrieves expressed GST fusion protein in soluble form after lysis and extraction procedures.... read more
Recombinant proteins expressed in bacteria often form inclusion bodies especially when they are expressed at high levels. Creative BioMart retrieves expressed GST fusion protein in soluble form after lysis and extraction procedures.... read more
45-1 Ramsey Road, Shirley, New York 11967, USA, Shirley
Creative BioMart is a leader in applying directed molecular evolution to improve healthcare by discovering optimizing and developing human biotherapeutics.... read more
Creative BioMart is a leader in applying directed molecular evolution to improve healthcare by discovering optimizing and developing human biotherapeutics.... read more
45-1 Ramsey Road, Shirley, New York 11967, USA, Shirley
Creative BioMart has been working with pharmaceutical biotechnology and academic customers and collaborators since its founding providing membrane protein-related products and services that advance its customers’ scientific objectives.... read more
Creative BioMart has been working with pharmaceutical biotechnology and academic customers and collaborators since its founding providing membrane protein-related products and services that advance its customers’ scientific objectives.... read more
45-1 Ramsey Road, Shirley, New York 11967, USA, Shirley
Enzymes are attractive targets for pharmacological intervention owing to their essential roles in life processes and pathophysiology. Because of their critical roles in the study of drug metabolism pharmacokinetics and toxicity reactions the demand for the new enzyme assay development is increasing. Creative BioMart is committed to developing a variety of comprehensive assays. In addition to the popular kinase and protease assay panels Creative BioMart offers miscellaneous enzyme assay services including but not limited to lipases oxidoreductases deacetylases CYP450 enzymes and phosphodiesterases (PDE) all of which have been identified as prospective druggable entities.... read more
Enzymes are attractive targets for pharmacological intervention owing to their essential roles in life processes and pathophysiology. Because of their critical roles in the study of drug metabolism pharmacokinetics and toxicity reactions the demand for the new enzyme assay development is increasing. Creative BioMart is committed to developing a variety of comprehensive assays. In addition to the popular kinase and protease assay panels Creative BioMart offers miscellaneous enzyme assay services including but not limited to lipases oxidoreductases deacetylases CYP450 enzymes and phosphodiesterases (PDE) all of which have been identified as prospective druggable entities.... read more
45-1 Ramsey Road, Shirley, New York 11967, USA, Shirley
Dynamins represent one of the subfamilies of GTP-binding proteins. These proteins share considerable sequence similarity over the N-terminal portion of the molecule which contains the GTPase domain. Dynamins are associated with microtubules. They have been implicated in cell processes such as endocytosis and cell motility and in alterations of the membrane that accompany certain activities such as bone resorption by osteoclasts. Dynamins bind many proteins that bind actin and other cytoskeletal proteins. Dynamins can also self-assemble a process that stimulates GTPase activity. Five alternatively spliced transcripts encoding different proteins have been described. Additional alternatively spliced transcripts may exist but their... read more
Dynamins represent one of the subfamilies of GTP-binding proteins. These proteins share considerable sequence similarity over the N-terminal portion of the molecule which contains the GTPase domain. Dynamins are associated with microtubules. They have been implicated in cell processes such as endocytosis and cell motility and in alterations of the membrane that accompany certain activities such as bone resorption by osteoclasts. Dynamins bind many proteins that bind actin and other cytoskeletal proteins. Dynamins can also self-assemble a process that stimulates GTPase activity. Five alternatively spliced transcripts encoding different proteins have been described. Additional alternatively spliced transcripts may exist but their... read more
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