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Mammalian Expression Systems

45-1 Ramsey Road, Shirley, New York 11967, USA, Shirley
Mammalian cell expression systems are the best choice for the production of eukaryotic proteins especially when correct folding and post-translational modification (glycosylation phosphorylation etc.) is required. They produce eukaryotic recombinant proteins in the most natural state with native tertiary structure physiochemical characteristics and bioactivities. They have been successfully applied in the biopharmaceutical production of cytokines monoclonal antibodies growth factors and so on. The most widely-used mammalian cell lines are HEK293 and CHO cells.... read more

HEK293 expression

Yeast Expression Systems

45-1 Ramsey Road, Shirley, New York 11967, USA, Shirley
Yeast is the simplest eukaryotic expression system. It sustains post-translational modification and proper folding of eukaryotic proteins while still allows easy culture and scale-up production at relatively low cost. The two most commonly used yeast species are Saccharomyces cerevisiae and Pichia pastoris.... read more

Bacterial Expression Systems

45-1 Ramsey Road, Shirley, New York 11967, USA, Shirley
Bacteria are the most widely used protein expression systems for their rapid growth high yield ease of manipulation and scale-up. The most widely used bacteria host is of course Escherichia coli. E. coli is the most established tool and is almost always the first choice if applicable. Profacgen offers various E. coli strains and expression vectors to seek for high-quality and high-level production of your target proteins.... read more

Protein Expression

45-1 Ramsey Road, Shirley, New York 11967, USA, Shirley
Recombinant protein expression is the technique of target protein production using the recombinant DNA technology. It is now commonly used in bioresearch and in pharmaceutical production of recombinant protein therapeutics. The recombinant DNA usually the cDNA sequence of the target protein is designed to be under the control of a well characterized promoter and express the target protein within the chosen host cell to achieve high-level protein expression.... read more

Protein Phosphorylation Site Mapping

45-1 Ramsey Road, Shirley, New York 11967, USA, Shirley
Creative BioMart provides for the detection of phosphosites located in a target protein that has been phosphorylated in vivo and purified by immuno-precipitation or a recombinant protein that has been phosphorylated in vitro with a purified protein kinase.... read more

Kinase Assay

45-1 Ramsey Road, Shirley, New York 11967, USA, Shirley
Creative BioMart offers the widest and most comprehensive breadth of technologies available to screen for kinase enzyme activity. This portfolio consists of technologies that range from homogenous assays utilizing peptide substrates to antibody specific assays.... read more

IL15RA

45-1 Ramsey Road, Shirley, New York 11967, USA, Shirley
This gene encodes a cytokine receptor that specifically binds interleukin 15 (IL15) with high affinity. The receptors of IL15 and IL2 share two subunits IL2R beta and IL2R gamma. This forms the basis of many overlapping biological activities of IL15 and... read more

Il10

45-1 Ramsey Road, Shirley, New York 11967, USA, Shirley
Official Full Nameinterleukin 10 Backgroundfactor involved in the inhibition of cytokine synthesis [RGD Feb 2006] SynonymsIL10; interleukin 10; IL10X; interleukin-10; CSIF; IL-10; cytokine synthesis inhibitory factor;... read more

IGFBP6

45-1 Ramsey Road, Shirley, New York 11967, USA, Shirley
Official Full NameIGFBP6 insulin-like growth factor binding protein 6 SynonymsIGFBP6; insulin-like growth factor binding protein 6; insulin-like growth factor-binding protein 6; IBP-6; IGFBP-6; IGF binding protein 6; IGF-binding protein 6; IBP6;... read more

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