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1,449 RESULTS WITHIN anywhere FROM https:, India
Liposome in Cosmetics
45-1 Ramsey Road, Shirley, New York 11967, USA, Shirley
Consumers are more focused on their health and appearance than ever before. This trend creates an increasing demand for functional cosmetics ingredients and efficient delivery systems. Known for high performance and efficient development in liposome delivery systems Creative Biostructure has extended the applications into the cosmetic industry. Why use liposomes in cosmetics? Liposomes are most widely known as spherical vesicles composed of phospholipids with an aqueous core that can be used as the delivery vehicle. For example some studies suggested that liposomes facilitate the passage of active ingredient across the stratum corneum and transport them to the deep layers of... read more
Liposome in Food Industry
45-1 Ramsey Road, Shirley, New York 11967, USA, Shirley
Creative Biostructure has committed to the research and development of liposome technology in the past decade and has established a comprehensive liposome platform specialized in food-related applications. Why use liposomes in food industry? Liposomes have great potentials in the food beverage and nutraceutical industries as shown in published precedent. In food industry the application of liposomes mainly focuses on texture alteration and water retention improvement. Liposomes can encapsulate various components such as additives preservatives and antimicrobials resulting in enriched flavors and increased bioavailability of the contents. Liposomes are particularly suitable for the food industry as they provide natural non-toxic biodegradable... read more
Liposome Characterization
45-1 Ramsey Road, Shirley, New York 11967, USA, Shirley
Creative Biostructure utilizes a wide range of techniques for liposome analysis based on our comprehensive Liposome Platform. Determination of various liposome properties are often desired during development of a specific product or process.... read more
Transfersome Production
45-1 Ramsey Road, Shirley, New York 11967, USA, Shirley
Creative Biostructure offers liposome manufacturing services to elevate the current industrial standard with our cutting-edge technologies and approaches. Our experts are specialized in liposome manufacturing and characterization and have already established the transfersome platform to transport drug through skin. How Transfersomes Work Different from other types of liposomes transfersomes are mainly developed for transdermal drug delivery systems. Transfersomes are composed of self-assembled phospholipids (eg. phosphatidylcholine) and edge activators (such as a biocompatible surfactant or an amphiphilic drug) which increases lipid bilayer flexibility and permeability. Therefore transfersomes can deform and pass through narrow constriction (from 5 to 10 times less than... read more
GLP Compliant Protein Production
Ramsey Road, Shirley, New York 11967, USA, Shirley
Profacgen is capable of providing professional GLP Compliant Protein Production service to accelerate our customer’s preclinical drug development process. GLP (Good Laboratory Practice) refers to a set of principles that provides a framework for studies that are planned performed recorded reported archived and monitored. GLP-validated assays and manufacturing services under GLP guidelines help assure regulatory authorities that the data submitted are a true reflection of the results obtained from preclinical study and therefore can be relied upon when making safety assessments.... read more
Process Development Service
45-1 Ramsey Road, Shirley, New York 11967, USA, Shirley
Profacgen is capable of providing process development service for our customers. We have extensive expertise in all aspects of upstream and downstream development of protein drug/product manufacturing process which facilitates your preclinical drug development process. We guarantee the well-defined scalable and reproducible processes of making successful protein products are undertaken in a commercially viable and regulatory compliant way. Process Development Service In general Process Development service involves cell line development and selection upstream process development and downstream purification process development. At Profacgen we can screen among production strains to select an appropriate cell line that will efficiently produce your drug... read more
Pharmacophore Modeling
45-1 Ramsey Road, Shirley, New York 11967, USA, Shirley
Pharmacophore approaches are successful subfields of computer-aided drug design (CADD) which have become one of the major tools in hit identification lead optimization and rational design of novel drugs. A pharmacophore model is the ensemble of common steric and electronic features that are necessary to ensure the optimal molecular interactions with a specific biological target and to trigger (or block) its biological response. It can be used to represent and characterize molecules on schematic 2D or 3D level by identifying the essential properties of molecular recognition. Every type of atom or group in a compound can be reduced to a... read more
ADME Prediction
45-1 Ramsey Road, Shirley, New York 11967, USA, Shirley
Profacgen strives to provide computational predictions of ADME toxicological and physicochemical properties as well as the analysis and interpretation of the predicted data. We take advantage of the most state-of-the-art ADME and Tox property prediction computational methods and software tools to quickly and accurately predict over 100 properties including solubility logP and pKa etc.... read more
Quantum Mechanics in Drug Design
45-1 Ramsey Road, Shirley, New York 11967, USA, Shirley
Profacgen provides QM calculation service to describe the protein system including ligands and solvent in order to gain a better understanding of protein-ligand interactions with improved accuracy. The utility of QM can provide accurate force field parameters from results of ab initio calculations on small model structures. It can also explicitly describe the electronic structure of a molecule.... read more
3D QSAR
45-1 Ramsey Road, Shirley, New York 11967, USA, Shirley
Profacgen provides 3D-QSAR pipeline that enables researchers to effectively perform force field calculations requiring three-dimensional structures of a training set (with known activities measured experimentally). The created data space is then reduced by feature extraction and a following machine learning method. Our workflow includes biological data analysis optimization of 3D structure of the biomolecules determination of bioactive conformations of biomolecules calculation of molecular interaction energy fields 3D QSAR model generation and validation etc. This one-step 3D-QSAR workflow aims to help researchers identify determinants for biological activities of small molecules optimize existing leads for improved activities and predict the biological activities... read more
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