Peptides
124 RESULTS WITHIN anywhere FROM https:, United States
Distance: 12,798.63km
45-16 Ramsey Road, Shirley, NY 11967, USA, Shirley, NY
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Glucagon-like peptide-1(7–36) amide (GLP-1) a peptide secreted from intestinal enteroendocrine L cells control systemic blood glucose homeostasis in humans after a meal. Therapies based on the GLP-1 are novel treatment options for type 2 diabetes that act through a variety of complementary mechanisms. Unlike other diabetes drugs the insulinotropic effect of GLP-1 is self-limiting as it falls once the plasma glucose level is lowered to normal range reducing the risk of hypoglycemia. In addition GLP-1 regulates postprandial glucose elevation through several other mechanisms including promoting insulin gene transcription stimulating pancreatic β-cell proliferation and neogenesis inhibiting β-cell apoptosis and blocking glucagon... read more
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Glucagon-like peptide-1(7–36) amide (GLP-1) a peptide secreted from intestinal enteroendocrine L cells control systemic blood glucose homeostasis in humans after a meal. Therapies based on the GLP-1 are novel treatment options for type 2 diabetes that act through a variety of complementary mechanisms. Unlike other diabetes drugs the insulinotropic effect of GLP-1 is self-limiting as it falls once the plasma glucose level is lowered to normal range reducing the risk of hypoglycemia. In addition GLP-1 regulates postprandial glucose elevation through several other mechanisms including promoting insulin gene transcription stimulating pancreatic β-cell proliferation and neogenesis inhibiting β-cell apoptosis and blocking glucagon... read more
Distance: 12,798.63km
45-16 Ramsey Road, Shirley, NY 11967, USA, Shirley, NY
Tel:
De novo design is an attractive approach for constructing designed peptides with predetermined structures and functions. Creative Peptides provides de novo design related services for peptides engineering including peptides structure prediction peptides folding and interactions thermodynamics information energetic state stability etc. De novo design requires deep understanding of the structure of a peptide and the correlated functions. It is accomplished either from scratch or by the modular approach. Creative Peptides provides de novo design related services for peptides engineering including peptides structure prediction peptides folding and interactions thermodynamics information energetic state stability etc. If you would like Creative peptides to... read more
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De novo design is an attractive approach for constructing designed peptides with predetermined structures and functions. Creative Peptides provides de novo design related services for peptides engineering including peptides structure prediction peptides folding and interactions thermodynamics information energetic state stability etc. De novo design requires deep understanding of the structure of a peptide and the correlated functions. It is accomplished either from scratch or by the modular approach. Creative Peptides provides de novo design related services for peptides engineering including peptides structure prediction peptides folding and interactions thermodynamics information energetic state stability etc. If you would like Creative peptides to... read more
Distance: 12,798.63km
45-16 Ramsey Road, Shirley, NY 11967, USA, Shirley, NY
What is stabled peptide Stapled peptide is a full-carbon scaffold with an α-helical structure. The all-carbon scaffold stabilizes the α-helical structure enhances the interaction between the peptide molecule and the protein and the peptide can pass through the cell membrane and is not easily hydrolyzed. Stapled peptides have higher physiological activity than previous small molecule drugs and protein analogs. Advantages of Custom Stapled Peptides • Better target affinity • Increased proteolytic resistance and serum half- life • Increased cell permeability • Targeting of either extracellular or intracellular proteins • Non-immunogenicity • Viable pharmacokinetics and in vivo stability Creative Peptides provides... read more
What is stabled peptide Stapled peptide is a full-carbon scaffold with an α-helical structure. The all-carbon scaffold stabilizes the α-helical structure enhances the interaction between the peptide molecule and the protein and the peptide can pass through the cell membrane and is not easily hydrolyzed. Stapled peptides have higher physiological activity than previous small molecule drugs and protein analogs. Advantages of Custom Stapled Peptides • Better target affinity • Increased proteolytic resistance and serum half- life • Increased cell permeability • Targeting of either extracellular or intracellular proteins • Non-immunogenicity • Viable pharmacokinetics and in vivo stability Creative Peptides provides... read more
Distance: 12,798.63km
45-16 Ramsey Road, Shirley, NY 11967, USA, Shirley, NY
Cyclic peptide compounds are a class of cyclic compounds with special structure widely biological activity and unique mechanism of action which play an important role in natural products. Cyclic peptides are compounds of stable and uniform conformation in peptide molecules which have high selective affinity for receptors strong metabolic stability and high oral availability. As a drug molecule a cyclic peptide compound has a wide range of biological activities such as anticancer antiviral antibacterial antifungal and enzyme inhibitors. Therefore research on cyclic peptide drugs is receiving more and more attention. Cyclic peptide synthesis has proven to be useful for several... read more
Cyclic peptide compounds are a class of cyclic compounds with special structure widely biological activity and unique mechanism of action which play an important role in natural products. Cyclic peptides are compounds of stable and uniform conformation in peptide molecules which have high selective affinity for receptors strong metabolic stability and high oral availability. As a drug molecule a cyclic peptide compound has a wide range of biological activities such as anticancer antiviral antibacterial antifungal and enzyme inhibitors. Therefore research on cyclic peptide drugs is receiving more and more attention. Cyclic peptide synthesis has proven to be useful for several... read more
Distance: 12,798.63km
315 West Elliott Road, Suite 107-196, Tempe
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Distance: 12,798.63km
45-16 Ramsey Road, Shirley, NY 11967, USA, Shirley, NY
Tel:
Synthesis challenges and strategies of long peptides There are some challenges to the synthesis of long peptides such as a large cumulative effect of yield which can result in slow or incomplete coupling and/or reverse protection during the synthesis as well as low solubility in the assembly of the protected peptide. For the synthesis of long peptides there are generally two ways of gradual growth and fragment condensation. The former starts with the starting amino acid (or peptide) and grows one amino acid per connection. The latter is obtained by condensation of a C-terminal protective peptide and an N-terminal protective... read more
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Synthesis challenges and strategies of long peptides There are some challenges to the synthesis of long peptides such as a large cumulative effect of yield which can result in slow or incomplete coupling and/or reverse protection during the synthesis as well as low solubility in the assembly of the protected peptide. For the synthesis of long peptides there are generally two ways of gradual growth and fragment condensation. The former starts with the starting amino acid (or peptide) and grows one amino acid per connection. The latter is obtained by condensation of a C-terminal protective peptide and an N-terminal protective... read more
Distance: 12,798.63km
45-16 Ramsey Road, Shirley, NY 11967, USA, Shirley, NY
Tel: 0631 619 7922
Peptide antigen namely a peptide used to trigger animal's immune system to develop antibodies specific to that peptide. Nowadays the use of synthetic peptide antigens as immunogens has markedly increased and this technique is also widely applied for immune research such as tumor immunotherapy etc. With ten years experience in antigen peptides supply Creative Peptides is experienced in the synthesis of complex antigen peptides such as glycopeptides or hyperphosphorylation peptides. Design of peptide antigens Although many peptide sequences are immunogenic not all of them are identically effective in generating antibodies when act against the target protein. Effective antibody generation depends... read more
Tel: 0631 619 7922
Peptide antigen namely a peptide used to trigger animal's immune system to develop antibodies specific to that peptide. Nowadays the use of synthetic peptide antigens as immunogens has markedly increased and this technique is also widely applied for immune research such as tumor immunotherapy etc. With ten years experience in antigen peptides supply Creative Peptides is experienced in the synthesis of complex antigen peptides such as glycopeptides or hyperphosphorylation peptides. Design of peptide antigens Although many peptide sequences are immunogenic not all of them are identically effective in generating antibodies when act against the target protein. Effective antibody generation depends... read more
Distance: 12,798.63km
45-16 Ramsey Road, Shirley, NY 11967, USA, Shirley, NY
DOTA is an organic compound and commonly used as a complexing agent which has been widely used as contrast agent for cancer treatments. It can also be linked to molecules that have affinity to various structures (e.g. somatostatin receptors on neuroendocrine tumours). The generated compounds may combine with a number of radioisotopes to be used in cancer therapy and diagnosis. Complexes of DOTA peptides depending on the metal ion have found applications in three major areas: magnetic resonance imaging [GdIII) Eu(III)] nuclear imaging [111In(III) 68Ga(III) 64/67Cu(II)] and therapeutic radiopharmaceuticals [90Y(III) 177Lu(III)]. For example DOTA could act as a chelator for... read more
DOTA is an organic compound and commonly used as a complexing agent which has been widely used as contrast agent for cancer treatments. It can also be linked to molecules that have affinity to various structures (e.g. somatostatin receptors on neuroendocrine tumours). The generated compounds may combine with a number of radioisotopes to be used in cancer therapy and diagnosis. Complexes of DOTA peptides depending on the metal ion have found applications in three major areas: magnetic resonance imaging [GdIII) Eu(III)] nuclear imaging [111In(III) 68Ga(III) 64/67Cu(II)] and therapeutic radiopharmaceuticals [90Y(III) 177Lu(III)]. For example DOTA could act as a chelator for... read more
Distance: 12,798.63km
45-16 Ramsey Road, Shirley, NY 11967, USA, Shirley, NY
Tel: 0631 619 7922
Creative Peptides is one of the world's largest producers of synthetic peptides. We have cGMP certified manufacturing facilities and expertise that provide us the ability to produce non-GMP grade and GMP grade peptides from miligram quantities to commercial requirements of multi-kilograms or more. The advantage of manufacturing active pharmaceutical ingredients at a low-cost makes Creative Peptides stand out among international API manufacturers. Services we offer: Vaccine Target Identification. Epitope& Neo Epitope Discovery/ Validation. Immunogenic & Multiple antigenic Peptides Synthesis. Immune Monitoring. DNA and RNA sequencing of peripheral blood mononuclear cells of a cancer patient for detection of tumor-specific mutations. Translation... read more
Tel: 0631 619 7922
Creative Peptides is one of the world's largest producers of synthetic peptides. We have cGMP certified manufacturing facilities and expertise that provide us the ability to produce non-GMP grade and GMP grade peptides from miligram quantities to commercial requirements of multi-kilograms or more. The advantage of manufacturing active pharmaceutical ingredients at a low-cost makes Creative Peptides stand out among international API manufacturers. Services we offer: Vaccine Target Identification. Epitope& Neo Epitope Discovery/ Validation. Immunogenic & Multiple antigenic Peptides Synthesis. Immune Monitoring. DNA and RNA sequencing of peripheral blood mononuclear cells of a cancer patient for detection of tumor-specific mutations. Translation... read more
Distance: 12,798.63km
45-16 Ramsey Road, Shirley, NY 11967, USA, New York
Creative Peptides provides quality services With more than 10 years of experience and as a world-leading peptide manufacturing organization Creative Peptides can provide customized peptides labeled with stable isotopes including 2H 15N & 13C respectively or a combination of 15N & 13C. Even when the peptides are attached with specific modification motifs. Services Features Design & synthesis of your peptides with expected mass difference by applying specific stable isotope-labeled amino acids Easy and efficient quantification of the natural peptide by MS assay Free of radioactive hazard Possible assorted modifications such as disulfide bond formation Quick analysis of biological samples with... read more
Creative Peptides provides quality services With more than 10 years of experience and as a world-leading peptide manufacturing organization Creative Peptides can provide customized peptides labeled with stable isotopes including 2H 15N & 13C respectively or a combination of 15N & 13C. Even when the peptides are attached with specific modification motifs. Services Features Design & synthesis of your peptides with expected mass difference by applying specific stable isotope-labeled amino acids Easy and efficient quantification of the natural peptide by MS assay Free of radioactive hazard Possible assorted modifications such as disulfide bond formation Quick analysis of biological samples with... read more
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