Introduction
As a pioneer and the undisrupted global leader in antibody discovery and engineering, Creative Biolabs proudly introduces our professional service of anti-membrane protein antibody discovery with our diverse technologies.
Membrane proteins, which consist of 20~30% of total encoding genes in the genome, play a critical role in multiple biological processes, including ligand-receptor binding, signal transduction, molecule transportation, intercellular recognition, and cell adhesion. Currently, there rises growing interest regarding membrane proteins as promising targets for various drug development and other applications.
To obtain highly functional anti-membrane protein antibodies, expression and presentation of the membrane protein of interest as immunogen is the prerequisite. As most membrane proteins are partially or completely embedded in the lipid bilayer, traditional expression methods meet obstacles in presenting the native conformations, such as low expression level, difficult extraction, misfolding, and incomplete post-translational modifications. With a full understanding of the critical requirements in this field, Creative Biolabs has developed a novel Magicâ„¢ platform, which enables high-efficient expression of membrane proteins and following antibody development routes based on our multiple impeccable technologies.
Membrane proteins, which consist of 20~30% of total encoding genes in the genome, play a critical role in multiple biological processes, including ligand-receptor binding, signal transduction, molecule transportation, intercellular recognition, and cell adhesion. Currently, there rises growing interest regarding membrane proteins as promising targets for various drug development and other applications.
To obtain highly functional anti-membrane protein antibodies, expression and presentation of the membrane protein of interest as immunogen is the prerequisite. As most membrane proteins are partially or completely embedded in the lipid bilayer, traditional expression methods meet obstacles in presenting the native conformations, such as low expression level, difficult extraction, misfolding, and incomplete post-translational modifications. With a full understanding of the critical requirements in this field, Creative Biolabs has developed a novel Magicâ„¢ platform, which enables high-efficient expression of membrane proteins and following antibody development routes based on our multiple impeccable technologies.
Contact Info
Address:
45-1 Ramsey Road, Shirley, NY 11967, USA
Shirley
Illinois 11967
United States
Shirley
Illinois 11967
United States
Tel:
Website:
https://www.creative-biolabs.com/membrane-protein-service.html
Hours of operation
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