Introduction
The CRISPR/Cas9 system is an adaptive immunity system in bacteria against bacteriophage invading. It has been developed as the most popular method for genome editing in recent years. The engineered CRISPR/Cas9 technology consists of a single guide RNA (sgRNA) and a human codon-optimized Cas9 nuclease. The sgRNA recognizes the genomic target via standard Watson–crick base pairing and acts as a scaffold for binding of the endonuclease Cas9. Then Cas9 protein introduces site-specific DSBs in the target DNA sequences. Besides, in the phase of target recognition, the protospacer-adjacent motif (PAM) adjacent to the 3’ end of the DNA target site is indispensable. Finally, targeted mutations can be induced by nonhomologous end joining (NHEJ).
Contact Info
Address:
45-1 Ramsey Road, Shirley, NY 11967, USA
Shirley
Illinois 11967
United States
Shirley
Illinois 11967
United States
Tel:
6316197922
Website:
https://www.creative-biogene.com/products/gene-knockout-stable-cell-lines.html
Offering
- knockout cell lines
Hours of operation
| From | To | From | To | From | To | ||
|---|---|---|---|---|---|---|---|
| Monday | Open | 9:00am | 5:00pm | ||||
| Tuesday | Open | 9:00am | 5:00pm | ||||
| Wednesday | Open | 9:00am | 5:00pm | ||||
| Thursday | Open | 9:00am | 5:00pm | ||||
| Friday | Open | 9:00am | 5:00pm | ||||
| Saturday | Open | 9:00am | 5:00pm | ||||
| Sunday | Open | ||||||
SIMILAR BUSINESSES NEARBY
