Introduction
Creative Biolabs is professional in producing Fab fragment antibodies using well established methods. We provide the most comprehensive list of Fab fragment antibodies.
A Fab fragment is a special antibody which consists of four domains: VH, CH1, VL and CL1. The Fab fragment has 440-450 amino acids and its molecular weight is about 47-48 kDa.
Compared with the full length antibodies, Fab fragments have some advantages. On one hand it is easy to penetrate tissues and can be generated by some simpler expression systems, such as E. coli. On the other hand, the Fab fragments lack Fc regions so that the interactions between Fc portions and Fc receptor will be removed. Therefore, the Fab fragments can enhance antibody specificity and reduce the effector functions. Fab fragment antibodies will become more and more important and popular.
A Fab fragment is a special antibody which consists of four domains: VH, CH1, VL and CL1. The Fab fragment has 440-450 amino acids and its molecular weight is about 47-48 kDa.
Compared with the full length antibodies, Fab fragments have some advantages. On one hand it is easy to penetrate tissues and can be generated by some simpler expression systems, such as E. coli. On the other hand, the Fab fragments lack Fc regions so that the interactions between Fc portions and Fc receptor will be removed. Therefore, the Fab fragments can enhance antibody specificity and reduce the effector functions. Fab fragment antibodies will become more and more important and popular.
Contact Info
Address:
45-1 Ramsey Road, Shirley, NY 11967, USA
Shirley
ILLINOIS 11967
United States
Shirley
ILLINOIS 11967
United States
Tel:
Website:
https://www.creativebiolabs.net/Fab-Fragment-Antibodies_24.htm
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