Introduction
Basic principles:
Surface Plasmon Resonance (SPR) is an optical detection process that occurs when a polarized light hits a prism covered by a thin planar metal (typically gold or silver) layer. At certain angles of incidence, a portion of the light energy couples through the gold coating and creates a surface plasmon wave at the sample and gold surface interface. The angle of incident light required to sustain the surface plasmon wave is very sensitive to changes in refractive index at the surface (due to mass change), and it is these changes that are used to monitor the association and dissociation of biomolecules.
Applications:
Kinetic characterization by Surface Plasmon Resonance and other methods has already been an important step for drug researchers to select and characterize novel therapeutics as well as for basic life scientists to investigate specific biological binding events. When combined with appropriate surface chemistry, microfluidics and software, SPRi is unmatched in its range of applications including:
Surface plasmon resonance imaging (SPRi) service
Affinity analysis
Kinetic analysis
Ligand-fishing
Epitope mapping
Protein / protein interaction
DNA/DNA interactions
Protein/carbohydrates
Protein / DNA interactions
RNA/RNA interactions
Antibody (protein) / bacteria interactions
Antibody / cell interactions
Peptide / protein interactions
Polymer / polymer interactions
Our Services
In conclusion, SPRi is a well-established leading technology for measuring binding association (ka) and dissociation rates (kd), affinities (KD). Creative Peptides offers SPRi (Surface Plasmon Resonance imaging) services including Biochip design and printing, Bio-interactions analysis (binding affinity and kinetic processes detection), Summary and analysis of the results. Typical SPRi services include:
Protein/protein interaction
Protein/carbohydrates interaction
Protein/DNA interactions
Antibody (protein)/bacteria interactions
Surface Plasmon Resonance (SPR) is an optical detection process that occurs when a polarized light hits a prism covered by a thin planar metal (typically gold or silver) layer. At certain angles of incidence, a portion of the light energy couples through the gold coating and creates a surface plasmon wave at the sample and gold surface interface. The angle of incident light required to sustain the surface plasmon wave is very sensitive to changes in refractive index at the surface (due to mass change), and it is these changes that are used to monitor the association and dissociation of biomolecules.
Applications:
Kinetic characterization by Surface Plasmon Resonance and other methods has already been an important step for drug researchers to select and characterize novel therapeutics as well as for basic life scientists to investigate specific biological binding events. When combined with appropriate surface chemistry, microfluidics and software, SPRi is unmatched in its range of applications including:
Surface plasmon resonance imaging (SPRi) service
Affinity analysis
Kinetic analysis
Ligand-fishing
Epitope mapping
Protein / protein interaction
DNA/DNA interactions
Protein/carbohydrates
Protein / DNA interactions
RNA/RNA interactions
Antibody (protein) / bacteria interactions
Antibody / cell interactions
Peptide / protein interactions
Polymer / polymer interactions
Our Services
In conclusion, SPRi is a well-established leading technology for measuring binding association (ka) and dissociation rates (kd), affinities (KD). Creative Peptides offers SPRi (Surface Plasmon Resonance imaging) services including Biochip design and printing, Bio-interactions analysis (binding affinity and kinetic processes detection), Summary and analysis of the results. Typical SPRi services include:
Protein/protein interaction
Protein/carbohydrates interaction
Protein/DNA interactions
Antibody (protein)/bacteria interactions
Contact Info
Address:
45-16 Ramsey Road, Shirley, NY 11967, USA
Shirley, NY
NY 11967
United States
Shirley, NY
NY 11967
United States
Tel:
Website:
https://www.creative-peptides.com/services/surface-plasmon-resonance-imaging-spri-service.html
Hours of operation
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