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What is Stendra?
Stendra (avanafil) relaxes muscles found in the walls of blood vessels and increases blood flow to particular areas of the body.

Stendra is a second generation PDE-5 inhibitor that selectively targets the PDE-5 isoenzyme, the key protein in your body that contributes to ED. Because it primarily targets PDE-5, it has a low rate of side effects, is fast-acting*, and is flexible with food and alcohol consumption.

Typical ED meds also target other PDE enzymes such as PDE-1, PDE-3, PDE-6, and PDE-11, causing an increased risk in unwelcome side effects like impaired vision or low blood pressure.

Avanafil occurs as white crystalline powder, molecular formula C23H26ClN7O3 and molecular weight of 483.95 and is slightly soluble in ethanol, practically insoluble in water, soluble in 0.1 mol/L hydrochloric acid. STENDRA, for oral administration, is supplied as oval, pale yellow tablets containing 50 mg, 100 mg, or 200 mg avanafil debossed with dosage strengths. In addition to the active ingredient, avanafil, each tablet contains the following inactive ingredients: mannitol, fumaric acid, hydroxypropylcellulose, low substituted hydroxypropylcellulose, calcium carbonate, magnesium stearate, and ferric oxide yellow.

INDICATIONS:
STENDRA is a phosphodiesterase 5 (PDE5) inhibitor indicated for the treatment of erectile dysfunction.

DOSAGE AND ADMINISTRATION

Erectile Dysfunction

The recommended starting dose is 100 mg. STENDRA should be taken orally as needed as early as approximately 15 minutes before sexual activity.

Based on individual efficacy and tolerability, the dose may be increased to 200 mg taken as early as approximately 15 minutes before sexual activity, or decreased to 50 mg taken approximately 30 minutes before sexual activity. The lowest dose that provides benefit should be used.

The maximum recommended dosing frequency is once per day. Sexual stimulation is required for a response to treatment.

Use With Food:
STENDRA may be taken with or without food.

Stendra is used to treat erectile dysfunction (impotence).

Dosage Forms And Strengths
STENDRA (avanafil) is supplied as oval, pale yellow tablets containing 50 mg, 100 mg, or 200 mg avanafil debossed with dosage strength.

Precautions Of Avanafil:

*If you have an erection that lasts more than 4 hours, get medical help right away.

*Limit alcohol consumption to 3 servings when taking STENDRA. Drinking too much alcohol when taking STENDRA can increase your heart rate, lower blood pressure, and increase your chances of getting a headache or getting dizzy.

*Stendra should not be taken by a woman or a child.





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