Introduction
Introducing polyethylene glycol (PEG) to biomolecules and pharmaceuticals is known to enhance stability and pharmacological properties of proteins, peptides, antibody-drug conjugates and small-molecule drugs. As a synthetic polymer with high hydrophilicity, PEG is widely used to prolong circulation time of proteins, increase aqueous solubility of therapeutic molecules and reduce immunogenicity of biopharmaceuticals. To date, PEGylation has been successfully used in 12 marketed drugs.1 The PEGylation technology, first used in protein modification, has been recently transferred to small-molecule drugs, leading to a new wave of investigation in pharmaceutical industry.
Contact Info
Address:
45-1 Ramsey Road, Shirley, New York 11967, USA
Shirley
New York 11967
United States
Shirley
New York 11967
United States
Tel:
Website:
https://www.profacgen.com/pegylation-services.htm
Hours of operation
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