Introduction
An overview of PKA
PKA is a tetramer containing regulatory subunits and catalytic subunits with four regulatory subtypes (RIα, RIβ, RIIα, RIIβ) and three catalytic subtypes (Cα, Cβ, Cγ). PKA belongs to the serine/threonine protein kinase. In the AC-cAMP-PKACREB pathway, adenylate cyclase (AC) catalyzes the production of cyclic adenosine monophosphate (cAMP) by intracellular ATP. As an intracellular signaling substance, cAMP is mainly activated by PKA to realize signal transduction. Its functions involve many aspects including the plasticity of synapse, exocytosis and gene transcription. PKA is expressed throughout the brain, especially in the cerebral cortex, thalamus, and amygdala. Moreover, it is moderately expressed in the midbrain, nucleus accumbens, and ventral tegmental areas.
PKA is a tetramer containing regulatory subunits and catalytic subunits with four regulatory subtypes (RIα, RIβ, RIIα, RIIβ) and three catalytic subtypes (Cα, Cβ, Cγ). PKA belongs to the serine/threonine protein kinase. In the AC-cAMP-PKACREB pathway, adenylate cyclase (AC) catalyzes the production of cyclic adenosine monophosphate (cAMP) by intracellular ATP. As an intracellular signaling substance, cAMP is mainly activated by PKA to realize signal transduction. Its functions involve many aspects including the plasticity of synapse, exocytosis and gene transcription. PKA is expressed throughout the brain, especially in the cerebral cortex, thalamus, and amygdala. Moreover, it is moderately expressed in the midbrain, nucleus accumbens, and ventral tegmental areas.
Contact Info
Address:
45-16 Ramsey Road, Shirley, NY 11967, USA
Shirley, NY
New York 11967
United States
Shirley, NY
New York 11967
United States
Tel:
6316197922
Website:
https://www.bocsci.com/tag/pka-485.html
Hours of operation
| From | To | From | To | From | To | ||
|---|---|---|---|---|---|---|---|
| Monday | Open | ||||||
| Tuesday | Open | ||||||
| Wednesday | Open | ||||||
| Thursday | Open | ||||||
| Friday | Open | ||||||
| Saturday | Open | ||||||
| Sunday | Open | ||||||
