Introduction
Gene Therapy
Gene Therapy: A Promising Treatment for Alzheimer’s Disease
Genetic mutation is an important factor that contributes to the pathogenesis and development of Alzheimer’s disease (AD). The genetic factors studied include the dominant mutations of genes encoding amyloid-β precursor protein (APP), presenilin 1 (PSEN1), and presenilin 2 (PSEN2). Additionally, more and more genes have been found to be potentially associated with AD, such as apolipoprotein E (APOE), glycogen synthase kinase 3 beta (GSK3B), dual specificity tyrosine-phosphorylation-regulated kinase 1A (DYRK1A), and Tau. Although many studies on the treatment of AD have not been successful, gene therapy is still considered as a potential way against AD, and some gene-therapy-based therapeutics have entered the clinical trial stage. Existing strategies for gene therapy against AD include gene inactivation, genetic modification, and immunoregulation, etc.
Gene Therapy: A Promising Treatment for Alzheimer’s Disease
Genetic mutation is an important factor that contributes to the pathogenesis and development of Alzheimer’s disease (AD). The genetic factors studied include the dominant mutations of genes encoding amyloid-β precursor protein (APP), presenilin 1 (PSEN1), and presenilin 2 (PSEN2). Additionally, more and more genes have been found to be potentially associated with AD, such as apolipoprotein E (APOE), glycogen synthase kinase 3 beta (GSK3B), dual specificity tyrosine-phosphorylation-regulated kinase 1A (DYRK1A), and Tau. Although many studies on the treatment of AD have not been successful, gene therapy is still considered as a potential way against AD, and some gene-therapy-based therapeutics have entered the clinical trial stage. Existing strategies for gene therapy against AD include gene inactivation, genetic modification, and immunoregulation, etc.
Contact Info
Address:
45-1 Ramsey Road, Shirley, New York 11967, USA
New York
11967
United States
New York
11967
United States
Tel:
1-6316197922
Website:
https://www.creativebiomart.net/alzheimacy/therapeutics/gene-therapy/
Hours of operation
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