Introduction
5 alpha Reductase
5α-Reductase inhibitors (5-ARIs) are a class of chemicals with antiandrogen effects, used primarily in the treatment of benign prostatic hyperplasia (BPH) (enlarged prostate) and androgenic alopecia (pattern hair loss). They are also used less commonly to treat hirsutism (excessive hair growth) in women. These agents inhibit the enzyme 5α-reductase, which is involved in the metabolic transformations of a variety of endogenous steroids. 5α-reductase inhibition is most known for preventing conversion of testosterone, the major androgen sex hormone, to the more potent dihydrotestosterone (DHT), in androgen-associated disorders.
Catalog Product Name CAS Number
CGP-53153 149281-19-6
164656-23-9 Dutasteride 164656-23-9
194979-95-8 AS-601811 194979-95-8
222989-99-3 Finasteride acetate 222989-99-3
98319-26-7 Finasteride 98319-26-7
5α-Reductase inhibitors (5-ARIs) are a class of chemicals with antiandrogen effects, used primarily in the treatment of benign prostatic hyperplasia (BPH) (enlarged prostate) and androgenic alopecia (pattern hair loss). They are also used less commonly to treat hirsutism (excessive hair growth) in women. These agents inhibit the enzyme 5α-reductase, which is involved in the metabolic transformations of a variety of endogenous steroids. 5α-reductase inhibition is most known for preventing conversion of testosterone, the major androgen sex hormone, to the more potent dihydrotestosterone (DHT), in androgen-associated disorders.
Catalog Product Name CAS Number
CGP-53153 149281-19-6
164656-23-9 Dutasteride 164656-23-9
194979-95-8 AS-601811 194979-95-8
222989-99-3 Finasteride acetate 222989-99-3
98319-26-7 Finasteride 98319-26-7
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