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c Kit Inhibitor
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c-Kit Inhibitor
45-16 Ramsey Road, Shirley, NY 11967, USA, Shirley, NY
c-Kit Mast/stem cell growth factor receptor (SCFR) also known as proto-oncogene c-Kit or tyrosine-protein kinase Kit or CD117 is a receptor protein-tyrosine kinase that acts as cell-surface receptor for the cytokine KITLG/SCF and plays important roles in gametogenesis hematopoiesis mast cell development and function and melanogenesis. c-Kit consists of an extracellular domain a transmembrane segment a juxtamembrane segment and a protein kinase domain that contains an insert of about 80 amino acid residues. Binding of stem cell factor to Kit results in receptor dimerization and activation of protein kinase activity. Catalog Product Name CAS Number 1048007-93-7Masitinib mesylate1048007-93-7 1123837-84-2Sitravatinib1123837-84-2 B0084-457687DCC-26181225278-16-9 152459-95-5Imatinib152459-95-5... read more
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