Notch Signaling Pathway
1 RESULTS
45-16 Ramsey Road, Shirley, NY 11967, USA, Shirley, NY
As a crucial cell signaling pathway in metazoan development the Notch signaling pathway controls cell fate decisions in many different tissues in multicellular organisms. The Notch signaling pathway is composed of the Notch receptor the Notch ligand (DSL protein) the CSL (CBF-1 Suppressor of hairless a combination of Lag) DNA-binding protein other effectors and the regulatory molecule of Notch. In 1917 Morgan discovered the Notch gene in mutant Drosophila which was named because a partial loss of function in the gene that caused a nick on the edge of the fruit fly. Mammals have four different Notch receptors (Notchl-4) and... read more
As a crucial cell signaling pathway in metazoan development the Notch signaling pathway controls cell fate decisions in many different tissues in multicellular organisms. The Notch signaling pathway is composed of the Notch receptor the Notch ligand (DSL protein) the CSL (CBF-1 Suppressor of hairless a combination of Lag) DNA-binding protein other effectors and the regulatory molecule of Notch. In 1917 Morgan discovered the Notch gene in mutant Drosophila which was named because a partial loss of function in the gene that caused a nick on the edge of the fruit fly. Mammals have four different Notch receptors (Notchl-4) and... read more
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