Native MS ADCs Analysis
1 RESULTS WITHIN anywhere FROM https:, Australia
155 Federal Street, Boston
As continuous development of Antibody-drug conjugates (ADCs) and the improving needs for precise determination of drug structure drug characterization technology has also been constantly updated. When the traditional mass spectrometer technology cannot fully meet the demand for precise determination of complex drugs the technology of non-variable character spectrum (Native MS) has emerged. Native MS has wide application such as measurement of drug to antibody ratio (DAR) of ADCs. ADCs drugs are divided into two kinds of drugs which are lysine and cysteine conjugated drugs. Determination of lysine-conjugated drugs is often based on the traditional RPLC/MS technology and the protein needs... read more
As continuous development of Antibody-drug conjugates (ADCs) and the improving needs for precise determination of drug structure drug characterization technology has also been constantly updated. When the traditional mass spectrometer technology cannot fully meet the demand for precise determination of complex drugs the technology of non-variable character spectrum (Native MS) has emerged. Native MS has wide application such as measurement of drug to antibody ratio (DAR) of ADCs. ADCs drugs are divided into two kinds of drugs which are lysine and cysteine conjugated drugs. Determination of lysine-conjugated drugs is often based on the traditional RPLC/MS technology and the protein needs... read more
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