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MHC class 2
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class="kwhl">MHC class 2
45-16 Ramsey Road, Shirley, NY 11967, USA, Shirley, NY
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Being curious about the unfamiliar members of the MHC family the Carter team focused on MHC-II in this new study. Similar to their MHC-I study they applied computational biology to data from the Cancer Genome Atlas (TCGA) which is a database established by the National Institutes of Health from genomic information from different human tumors of thousands of species. They scored MHC-II molecules in 5942 patient tumors for their ability to present 1018 cancer antigens in order to assess their CD4+ T cells. These researchers found that an antigen that is well recognized by a human MHC-II is less likely... read more
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