Chiral Synthesis
13 RESULTS
45-16 Ramsey Road, Shirley, NY 11967, USA, Shirley, NY
Tel: 0631 619 7922
Chiral synthesis (enantioselective synthesis also called asymmetric synthesis) is the synthesis of a compound by a method that favors the formation of a specific enantiomer or diastereomer. It is a key process in modern chemistry and is particularly important in the field of medicinal chemistry as the different enantiomers or diastereomers of a molecule often have different biological activity. BOC Sciences has assembled a world-class team of experts to bring extensive experience in diastereoselective and enantioselective synthesis at very large scale. We provide all the services like asymmetric catalysis chiral auxiliaries biocatalysis enantioselective organocatalysis chiral pool synthesis and chiral resolution... read more
Tel: 0631 619 7922
Chiral synthesis (enantioselective synthesis also called asymmetric synthesis) is the synthesis of a compound by a method that favors the formation of a specific enantiomer or diastereomer. It is a key process in modern chemistry and is particularly important in the field of medicinal chemistry as the different enantiomers or diastereomers of a molecule often have different biological activity. BOC Sciences has assembled a world-class team of experts to bring extensive experience in diastereoselective and enantioselective synthesis at very large scale. We provide all the services like asymmetric catalysis chiral auxiliaries biocatalysis enantioselective organocatalysis chiral pool synthesis and chiral resolution... read more
45-16 Ramsey Road, Shirley, NY 11967, USA, Shirley, NY
Tel:
Chiral synthesis (enantioselective synthesis also called asymmetric synthesis) is the synthesis of a compound by a method that favors the formation of a specific enantiomer or diastereomer. It is a key process in modern chemistry and is particularly important in the field of medicinal chemistry as the different enantiomers or diastereomers of a molecule often have different biological activity. BOC Sciences has assembled a world-class team of experts to bring extensive experience in diastereoselective and enantioselective synthesis at very large scale. We provide all the services like asymmetric catalysis chiral auxiliaries biocatalysis enantioselective organocatalysis chiral pool synthesis and chiral resolution... read more
Tel:
Chiral synthesis (enantioselective synthesis also called asymmetric synthesis) is the synthesis of a compound by a method that favors the formation of a specific enantiomer or diastereomer. It is a key process in modern chemistry and is particularly important in the field of medicinal chemistry as the different enantiomers or diastereomers of a molecule often have different biological activity. BOC Sciences has assembled a world-class team of experts to bring extensive experience in diastereoselective and enantioselective synthesis at very large scale. We provide all the services like asymmetric catalysis chiral auxiliaries biocatalysis enantioselective organocatalysis chiral pool synthesis and chiral resolution... read more
45-16 Ramsey Road, Shirley, NY 11967, USA, Shirley, NY
Tel:
A logical extension about the application of chiral ligands in stereoselective catalysis has been developed. In general ligands design in asymmetric catalysis is guided by several simple concepts and principles. For instance the design of chiral ligands is frequently based on C2-symmetry in order to reduce the number of diastereomeric intermediates and transition states which play a role in the catalytic cycle. This approach has been vindicated by the successful development of several large families of (“privilegedâ€) chiral ligands which nowadays belong to the basic “tool kit†of asymmetric catalysis such as chiral diphosphines salen derivatives and bisoxazolines. These privileged... read more
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A logical extension about the application of chiral ligands in stereoselective catalysis has been developed. In general ligands design in asymmetric catalysis is guided by several simple concepts and principles. For instance the design of chiral ligands is frequently based on C2-symmetry in order to reduce the number of diastereomeric intermediates and transition states which play a role in the catalytic cycle. This approach has been vindicated by the successful development of several large families of (“privilegedâ€) chiral ligands which nowadays belong to the basic “tool kit†of asymmetric catalysis such as chiral diphosphines salen derivatives and bisoxazolines. These privileged... read more
45-16 Ramsey Road, Shirley, NY 11967, USA, Shirley, NY
Tel: 16316197922
Chiral resolution as an important tool in the production of optically active drugs is a process for the separation of racemic compounds into their enantiomers in the aspect of stereochemistry. Particularly when the methods of stereospecific synthesis designed for one of the enantiomers at present lead generally to enhanced enantioselectivity not only the development of analytical methods for the chiral separation to control optical purity of a large number of pharmaceuticals/therapeutics administered today but also the development of methods for quantitative large-scale separation from their racemic or enantiomeric mixture are required and are the challenges for chemists and open wider... read more
Tel: 16316197922
Chiral resolution as an important tool in the production of optically active drugs is a process for the separation of racemic compounds into their enantiomers in the aspect of stereochemistry. Particularly when the methods of stereospecific synthesis designed for one of the enantiomers at present lead generally to enhanced enantioselectivity not only the development of analytical methods for the chiral separation to control optical purity of a large number of pharmaceuticals/therapeutics administered today but also the development of methods for quantitative large-scale separation from their racemic or enantiomeric mixture are required and are the challenges for chemists and open wider... read more
45-16 Ramsey Road, Shirley, NY 11967, USA, Shirley, NY
BOC Sciences can provide a number of nucleotide related services including but not limited to: Gene Synthesis and Cloning Service Gene Mutagenesis Service Oligonucleotide Synthesis Service DNA Methylation Analysis Services Plasmid DNA Production Service Gene Expression Service We have lots of compounds in stock and our existing libraries of building blocks alongside with our specialized expertise allow short cut access to any desired novel nucleotide structure. In short we are convinced that our custom nucleotides synthesis service will meet or exceed your expectations. For additional information and for peptide synthesis pricing please contact us!... read more
BOC Sciences can provide a number of nucleotide related services including but not limited to: Gene Synthesis and Cloning Service Gene Mutagenesis Service Oligonucleotide Synthesis Service DNA Methylation Analysis Services Plasmid DNA Production Service Gene Expression Service We have lots of compounds in stock and our existing libraries of building blocks alongside with our specialized expertise allow short cut access to any desired novel nucleotide structure. In short we are convinced that our custom nucleotides synthesis service will meet or exceed your expectations. For additional information and for peptide synthesis pricing please contact us!... read more
45-16 Ramsey Road, Shirley, NY 11967, USA, Shirley, NY
Application Nucleoside analogues are used as antiviral or anticancer agents in medicine. Several analogues of the sugar backbone exist in molecular biology which are more stable alternative nucleoside/nucleotide analogues including LNA morpholino PNA. Dideoxynucleotides are used in sequencing. These nucleotides possess the non-canonical sugar dideoxyribose which lacks 3’ hydroxyl group (which accepts the phosphate) therefore it cannot bond with the next base and terminates the chain. Our Services BOC Sciences is a leading biotechnology company which has years of professional and abundant experience in providing nucleoside synthesis service for customers all over the world. BOC Sciences’s sophisticated equipments advanced technologies... read more
Application Nucleoside analogues are used as antiviral or anticancer agents in medicine. Several analogues of the sugar backbone exist in molecular biology which are more stable alternative nucleoside/nucleotide analogues including LNA morpholino PNA. Dideoxynucleotides are used in sequencing. These nucleotides possess the non-canonical sugar dideoxyribose which lacks 3’ hydroxyl group (which accepts the phosphate) therefore it cannot bond with the next base and terminates the chain. Our Services BOC Sciences is a leading biotechnology company which has years of professional and abundant experience in providing nucleoside synthesis service for customers all over the world. BOC Sciences’s sophisticated equipments advanced technologies... read more
45-16 Ramsey Road, Shirley, NY 11967, USA, Shirley, NY
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BOC Sciences also provide labeling services regarding custom synthesis of compounds that containing carbohydrate constituents. Our scientists can synthesis singly labeled multiply labeled and mixed labeled carbohydrates nucleosides and related derivatives. At BOC Sciences we also offer carbohydrates and nucleosides in stock products including monosaccharides enzyme substrates D- and L- sugars oligosaccharides detergents and nucleosides. In additional to the services above BOC Sciences also offers conjugation of carbohydrate with peptides antibodies and proteins. Carbohydrate expertise means quick lead time Custom quantities tailored to your research needs Commitment to providing rare or specialty carbohydrate compounds Discounts on groups of related compounds... read more
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BOC Sciences also provide labeling services regarding custom synthesis of compounds that containing carbohydrate constituents. Our scientists can synthesis singly labeled multiply labeled and mixed labeled carbohydrates nucleosides and related derivatives. At BOC Sciences we also offer carbohydrates and nucleosides in stock products including monosaccharides enzyme substrates D- and L- sugars oligosaccharides detergents and nucleosides. In additional to the services above BOC Sciences also offers conjugation of carbohydrate with peptides antibodies and proteins. Carbohydrate expertise means quick lead time Custom quantities tailored to your research needs Commitment to providing rare or specialty carbohydrate compounds Discounts on groups of related compounds... read more
45-16 Ramsey Road, Shirley, NY 11967, USA, Shirley, NY
Insulin is a peptide hormone produced by beta cells of the pancreatic islets. It is the major hormone controlling critical energy functions such as glucose and lipid metabolism. Insulin signaling plays an important role in the physiological action of insulin. Insulin binds to its receptor inducing intracellular signal transduction through a series of intracellular signaling molecules activating signaling pathways reaching the effector and finally producing various physiological effects. Insulin action is mediated through the insulin receptor which is composed of two extracellular α subunits and two transmembrane β subunits linked together by disulphide bonds. Insulin activates the insulin receptor tyrosine... read more
Insulin is a peptide hormone produced by beta cells of the pancreatic islets. It is the major hormone controlling critical energy functions such as glucose and lipid metabolism. Insulin signaling plays an important role in the physiological action of insulin. Insulin binds to its receptor inducing intracellular signal transduction through a series of intracellular signaling molecules activating signaling pathways reaching the effector and finally producing various physiological effects. Insulin action is mediated through the insulin receptor which is composed of two extracellular α subunits and two transmembrane β subunits linked together by disulphide bonds. Insulin activates the insulin receptor tyrosine... read more
45-16 Ramsey Road, Shirley, NY 11967, USA, Shirley, NY
Overview of the IL-1 Receptor Signaling Pathway IL-1 is a cytokine produced by activated macrophages which mediates several physiological responses to infections and injuries including stimulation of thymocyte proliferation B-lymphocyte maturation and proliferation induction of acute-phase protein synthesis by hepatocytes and induction of fever. In addition to macrophages fibroblast keratinocytes comeal cell astrocytes and EBV-transformed B-lymphocytes are also capable of producing IL-1. Monocyte cell lines produce IL-1 after treatment with agents such as TPA and LPS. There are 11 members of the IL-1 family (IL-1F) of ligands including IL-1α IL-1β IL-1 receptor antagonist (IL-1Ra) etc. The main function of IL-1-type... read more
Overview of the IL-1 Receptor Signaling Pathway IL-1 is a cytokine produced by activated macrophages which mediates several physiological responses to infections and injuries including stimulation of thymocyte proliferation B-lymphocyte maturation and proliferation induction of acute-phase protein synthesis by hepatocytes and induction of fever. In addition to macrophages fibroblast keratinocytes comeal cell astrocytes and EBV-transformed B-lymphocytes are also capable of producing IL-1. Monocyte cell lines produce IL-1 after treatment with agents such as TPA and LPS. There are 11 members of the IL-1 family (IL-1F) of ligands including IL-1α IL-1β IL-1 receptor antagonist (IL-1Ra) etc. The main function of IL-1-type... read more
45-16 Ramsey Road, Shirley, NY 11967, USA, Shirley, NY
Tel:
Adenosine monophosphate-activated protein kinase (AMPK) consists of three major segments or “modulesâ€: the catalytic module the CBM and the nucleotide-binding module (also called “regulatory fragmentâ€). AMPK exists as a trimetric complex consisting of a catalytic subunit (α subunit) and two regulatory subunits (β and γ subunits). The activation loop of the α subunit resides at the interface between the catalytic and nucleotide-binding modules in close proximity to the C terminus of the β subunit and the CBS repeats of the γ subunit. The active form of AMPK i.e. phosphorylated AMP-activated protein kinase (p-AMPK) can down regulate the energy consuming process... read more
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Adenosine monophosphate-activated protein kinase (AMPK) consists of three major segments or “modulesâ€: the catalytic module the CBM and the nucleotide-binding module (also called “regulatory fragmentâ€). AMPK exists as a trimetric complex consisting of a catalytic subunit (α subunit) and two regulatory subunits (β and γ subunits). The activation loop of the α subunit resides at the interface between the catalytic and nucleotide-binding modules in close proximity to the C terminus of the β subunit and the CBS repeats of the γ subunit. The active form of AMPK i.e. phosphorylated AMP-activated protein kinase (p-AMPK) can down regulate the energy consuming process... read more
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