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The amount and type of dietary fibers in the diet has significant effects on the composition of the intestinal bacteria and thereby on the type and amount of SCFAs generated. Mostly the in vivo SCFAs production rates on different fibers are related to the intestinal SCFAs concentrations on different fibers diet. Though the cecal SCFAs concentration is available in most model organisms it is hard to get information about in vivo production rates. In contrast it is almost impossible to measure the cecal SCFAs concentration in humans’ intestines. So most of the time the cecal and colonic metabolism are evaluated... read more
The amount and type of dietary fibers in the diet has significant effects on the composition of the intestinal bacteria and thereby on the type and amount of SCFAs generated. Mostly the in vivo SCFAs production rates on different fibers are related to the intestinal SCFAs concentrations on different fibers diet. Though the cecal SCFAs concentration is available in most model organisms it is hard to get information about in vivo production rates. In contrast it is almost impossible to measure the cecal SCFAs concentration in humans’ intestines. So most of the time the cecal and colonic metabolism are evaluated... read more
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All plant cells can produce the essential molecules VLCFAs which are precursors or components of a large number of specialized metabolites generated in specific cell types. Catalyzed by the fatty acid elongation complex of four core enzymes localized in endoplasmic reticulum VLCFAs are elongated and two carbon units are added to the growing acyl chain. As these enzymes in Arabidopsis thaliana is identified and characterized it reveals that three of the four enzymes work as generalists producing all the VLCFAs needed in all metabolic pathways. The fourth component of the complex is the enzyme response for condensing. This unit determines... read more
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All plant cells can produce the essential molecules VLCFAs which are precursors or components of a large number of specialized metabolites generated in specific cell types. Catalyzed by the fatty acid elongation complex of four core enzymes localized in endoplasmic reticulum VLCFAs are elongated and two carbon units are added to the growing acyl chain. As these enzymes in Arabidopsis thaliana is identified and characterized it reveals that three of the four enzymes work as generalists producing all the VLCFAs needed in all metabolic pathways. The fourth component of the complex is the enzyme response for condensing. This unit determines... read more
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A branched-chain amino acid (BCAA) is an amino acid having aliphatic side-chains with a branch (a central carbon atom bound to three or more carbon atoms). Among the proteinogenic amino acids there are three BCAAs: leucine isoleucine and valine. Non-proteinogenic BCAAs include 2-aminoisobutyric acid. The three proteinogenic BCAAs are among the nine essential amino acids for humans accounting for 35% of the essential amino acids in muscle proteins and 40% of the preformed amino acids required by mammals. Synthesis for BCAAs occurs in all locations of plants within the plastids of the cell as determined by presence of mRNAs which... read more
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