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B Cell Differentiation
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B Cell Differentiation
45-1 Ramsey Road, Shirley, NY 11967, USA, Shirley
Tel: 16316197922
B cells are primarily generated from hematopoietic stem cells (CD34+CD19−) in the bone marrow (BM) except for B1 B cells. While B cells maturation occurs in stages characterized by successive rearrangements and expressions of IgH and IgL gene segments. The antigen-recognition molecules of B cells are the immunoglobulins (Ig). These proteins are produced by B cells in a vast range of antigen specificities each B cell producing immunoglobulin of a single specificity.... read more
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