Health / Pharmaceuticals
1,449 RESULTS WITHIN anywhere FROM https:, United States
45-1 Ramsey Road, Shirley, New York 11967, USA, Shirley
Creative Biostructure has years of experience in developing liposome formulations to provide efficient drug delivery platforms for various therapeutic agents including analgesics. Our expertise and superior resources will greatly assist your research in analgesics development.... read more
Creative Biostructure has years of experience in developing liposome formulations to provide efficient drug delivery platforms for various therapeutic agents including analgesics. Our expertise and superior resources will greatly assist your research in analgesics development.... read more
45-1 Ramsey Road, Shirley, New York 11967, USA, Shirley
Creative Biostructure has comprehensive platforms and technologies to support a wide range of liposome applications. An emerging value of liposomes is its use as multifunctional auxiliaries in textile industry. Creative Biostructure offers specialized services in liposome design and textile processing.... read more
Creative Biostructure has comprehensive platforms and technologies to support a wide range of liposome applications. An emerging value of liposomes is its use as multifunctional auxiliaries in textile industry. Creative Biostructure offers specialized services in liposome design and textile processing.... read more
45-1 Ramsey Road, Shirley, New York 11967, USA, Shirley
As an established expert in artificial liposomes manufacturing Creative Biostructure continues the effort in extending the customer population and developed a platform that is focused on transforming natural lipid droplets into biofuels. We provide substantial support to in vitro functional studies based on our advanced techniques and skills.... read more
As an established expert in artificial liposomes manufacturing Creative Biostructure continues the effort in extending the customer population and developed a platform that is focused on transforming natural lipid droplets into biofuels. We provide substantial support to in vitro functional studies based on our advanced techniques and skills.... read more
45-1 Ramsey Road, Shirley, New York 11967, USA, Shirley
As an expert in liposome manufacturing Creative Biostructure offers trusted services to clients worldwide with a focus on clinical and nonclinical liposome applications. As the awareness of environmental pressure has grown over the years there is an increasing demand for effective methods in environmental remediation. Recent studies have indicated that liposomes may serve as the next generation cleaner for fuel-contaminated sands and soils. It is also our duty as a CRO company to help the clients design and develop functionalized liposomes as remedies for our ecosystem.... read more
As an expert in liposome manufacturing Creative Biostructure offers trusted services to clients worldwide with a focus on clinical and nonclinical liposome applications. As the awareness of environmental pressure has grown over the years there is an increasing demand for effective methods in environmental remediation. Recent studies have indicated that liposomes may serve as the next generation cleaner for fuel-contaminated sands and soils. It is also our duty as a CRO company to help the clients design and develop functionalized liposomes as remedies for our ecosystem.... read more
45-1 Ramsey Road, Shirley, New York 11967, USA, Shirley
As an expert in liposome manufacturing Creative Biostructure offers trusted services to clients worldwide with a focus on clinical and nonclinical liposome applications. As the awareness of environmental pressure has grown over the years there is an increasing demand for effective methods in environmental remediation. Recent studies have indicated that liposomes may serve as the next generation cleaner for fuel-contaminated sands and soils. It is also our duty as a CRO company to help the clients design and develop functionalized liposomes as remedies for our ecosystem.... read more
As an expert in liposome manufacturing Creative Biostructure offers trusted services to clients worldwide with a focus on clinical and nonclinical liposome applications. As the awareness of environmental pressure has grown over the years there is an increasing demand for effective methods in environmental remediation. Recent studies have indicated that liposomes may serve as the next generation cleaner for fuel-contaminated sands and soils. It is also our duty as a CRO company to help the clients design and develop functionalized liposomes as remedies for our ecosystem.... read more
45-1 Ramsey Road, Shirley, New York 11967, USA, Shirley
Creative Biostructure possesses a plenty of liposome resources that facilitate liposome applications in large scales. Besides customizing liposomes for a specific use Creative Biostructure provides various liposome kits for customers to prepare liposomes on-site with more flexibility.... read more
Creative Biostructure possesses a plenty of liposome resources that facilitate liposome applications in large scales. Besides customizing liposomes for a specific use Creative Biostructure provides various liposome kits for customers to prepare liposomes on-site with more flexibility.... read more
45-1 Ramsey Road, Shirley, New York 11967, USA, Shirley
At Profacgen we predict these protein–carbohydrate interactions through the combination of a genetic conformational search algorithm coupled with an empirical free energy function specific for carbohydrates. Our docking procedure allows for a systematic exploration of the orientations and positions of carbohydrate ligand into a protein cavity (which is usually more open and less well defined compared to small molecule binding sites) and assesses free energies of complex formation. Experiment-derived constraints can also be applied to the docking protocol to restrict the search space for the sugar as well as the protein molecule. The energy function is specifically designed for carbohydrates... read more
At Profacgen we predict these protein–carbohydrate interactions through the combination of a genetic conformational search algorithm coupled with an empirical free energy function specific for carbohydrates. Our docking procedure allows for a systematic exploration of the orientations and positions of carbohydrate ligand into a protein cavity (which is usually more open and less well defined compared to small molecule binding sites) and assesses free energies of complex formation. Experiment-derived constraints can also be applied to the docking protocol to restrict the search space for the sugar as well as the protein molecule. The energy function is specifically designed for carbohydrates... read more
45-1 Ramsey Road, Shirley, New York 11967, USA, Shirley
Protein–lipid interactions are stabilized by the formation of intermolecular hydrogen bonds van der Waals interactions hydrophobic interactions and ionic bridges (especially aspartate or glutamate residues) between the protein and lipid ligand. Profacgen makes use of the state-of-the-art computational software tools to predict these protein–lipid interactions. The lipid binding sites of a protein can be deduced from its amino acid sequence and/or predicted from its three-dimensional structure using molecular docking protocols. Our docking method combines sequence and structure information and explores the most energetically favorable protein-lipid complex. The scoring function is specifically designed to allow for the prediction of lipid distortion... read more
Protein–lipid interactions are stabilized by the formation of intermolecular hydrogen bonds van der Waals interactions hydrophobic interactions and ionic bridges (especially aspartate or glutamate residues) between the protein and lipid ligand. Profacgen makes use of the state-of-the-art computational software tools to predict these protein–lipid interactions. The lipid binding sites of a protein can be deduced from its amino acid sequence and/or predicted from its three-dimensional structure using molecular docking protocols. Our docking method combines sequence and structure information and explores the most energetically favorable protein-lipid complex. The scoring function is specifically designed to allow for the prediction of lipid distortion... read more
45-1 Ramsey Road, Shirley, New York 11967, USA, Shirley
Profacgen employs computational docking techniques to search all possible binding modes in the translational and rotational space between an antibody (Fv Fab or full antibody) and its antigen with modeling of conformational changes of the variable loops upon complex formation. This is an important means for understanding the physicochemical forces that underlie macromolecular interactions and a working hypothesis can be build based on the docked complex guiding further experiments for the rational design of antibody-based therapeutics.... read more
Profacgen employs computational docking techniques to search all possible binding modes in the translational and rotational space between an antibody (Fv Fab or full antibody) and its antigen with modeling of conformational changes of the variable loops upon complex formation. This is an important means for understanding the physicochemical forces that underlie macromolecular interactions and a working hypothesis can be build based on the docked complex guiding further experiments for the rational design of antibody-based therapeutics.... read more
45-1 Ramsey Road, Shirley, New York 11967, USA, Shirley
Profacgen makes use of state-of-the-art docking software tools to model protein–peptide interactions and to predict the complex structure. The general modeling procedure is divided into two stages: (1) a global search is performed to predict the binding site at the protein receptor surface; (2) a flexible local docking method is used to fit the peptide structure into the known binding site. These two steps take into consideration the significant conformational changes upon binding of the two components. The peptide folding process is explicitly simulated in the docking protocol. When experimental or predicted data on binding site residues are available such... read more
Profacgen makes use of state-of-the-art docking software tools to model protein–peptide interactions and to predict the complex structure. The general modeling procedure is divided into two stages: (1) a global search is performed to predict the binding site at the protein receptor surface; (2) a flexible local docking method is used to fit the peptide structure into the known binding site. These two steps take into consideration the significant conformational changes upon binding of the two components. The peptide folding process is explicitly simulated in the docking protocol. When experimental or predicted data on binding site residues are available such... read more
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