Health / Pharmaceuticals
1,449 RESULTS WITHIN anywhere FROM https:, India
45-1 Ramsey Road, Shirley, NY 11967, USA, Shirley
Tel: 6316197922
Profacgen makes use of state-of-the-art docking software tools to find the relative transformation and conformation of the protein and nucleic acid involved in energetically favorable complex formation. The general procedures are: First a rigid body global search is performed and geometrically plausible protein–nucleic acid complex structures are generated. In this process user-defined restraints can be applied to limit the search space. The resulting models are scored and ranked using statistical potentials developed specifically for protein–RNA or protein–DNA complexes. The best-scored structures are then clustered and representatives of the largest clusters are selected for structural optimization by energy minimization before being... read more
Tel: 6316197922
Profacgen makes use of state-of-the-art docking software tools to find the relative transformation and conformation of the protein and nucleic acid involved in energetically favorable complex formation. The general procedures are: First a rigid body global search is performed and geometrically plausible protein–nucleic acid complex structures are generated. In this process user-defined restraints can be applied to limit the search space. The resulting models are scored and ranked using statistical potentials developed specifically for protein–RNA or protein–DNA complexes. The best-scored structures are then clustered and representatives of the largest clusters are selected for structural optimization by energy minimization before being... read more
45-1 Ramsey Road, Shirley, NY 11967, USA, Shirley
Tel: 6316197922
Profacgen studies molecular dynamics of protein systems using state-of-the-art software tools. The general workflow of our MD simulation service follows these steps: First a model system is selected in which missing segments are fixed and the protonation states determined. Then the system is energy minimized and equilibrated by solving Newton's equations of motion until the properties of the system no longer change with time. After equilibration a production run is performed for an appropriate period of time to output trajectories which are then analyzed for the properties of interest.... read more
Tel: 6316197922
Profacgen studies molecular dynamics of protein systems using state-of-the-art software tools. The general workflow of our MD simulation service follows these steps: First a model system is selected in which missing segments are fixed and the protonation states determined. Then the system is energy minimized and equilibrated by solving Newton's equations of motion until the properties of the system no longer change with time. After equilibration a production run is performed for an appropriate period of time to output trajectories which are then analyzed for the properties of interest.... read more
45-1 Ramsey Road, Shirley, NY 11967, USA, Shirley
Tel: 6316197922
Profacgen takes advantage of the homology modeling method to help customers predict the three-dimensional structure of proteins of interest. We have extensive experience with the modeling of various monomeric and oligomeric proteins. The resultant structural models are all quality validated and can be used for functional annotation of genes molecular docking and directing further experimental work such as protein engineering and drug design. https://www.profacgen.com/homology-modeling.htm... read more
Tel: 6316197922
Profacgen takes advantage of the homology modeling method to help customers predict the three-dimensional structure of proteins of interest. We have extensive experience with the modeling of various monomeric and oligomeric proteins. The resultant structural models are all quality validated and can be used for functional annotation of genes molecular docking and directing further experimental work such as protein engineering and drug design. https://www.profacgen.com/homology-modeling.htm... read more
45-1 Ramsey Road, Shirley, New York 1196, Shirley
Tel: 6316197922
G protein-coupled receptors (GPCRs) also known as seven-transmembrane domain receptors 7TM receptors heptahelical receptors serpentine receptor and G protein-linked receptors (GPLR) comprise a large protein family of transmembrane receptors that sense molecules outside the cell and activate inside signal transduction pathways and ultimately cellular responses. G protein-coupled receptors are found only in eukaryotes including yeast choanoflagellates and animals. The ligands that bind and activate these receptors include light-sensitive compounds odors pheromones hormones and neurotransmitters and vary in size from small molecules to peptides to large proteins. G protein-coupled receptors are involved in many diseases and are also the target of... read more
Tel: 6316197922
G protein-coupled receptors (GPCRs) also known as seven-transmembrane domain receptors 7TM receptors heptahelical receptors serpentine receptor and G protein-linked receptors (GPLR) comprise a large protein family of transmembrane receptors that sense molecules outside the cell and activate inside signal transduction pathways and ultimately cellular responses. G protein-coupled receptors are found only in eukaryotes including yeast choanoflagellates and animals. The ligands that bind and activate these receptors include light-sensitive compounds odors pheromones hormones and neurotransmitters and vary in size from small molecules to peptides to large proteins. G protein-coupled receptors are involved in many diseases and are also the target of... read more
45-1 Ramsey Road, Shirley, New York 1196, Shirley
Tel: 6316197922
Signal transduction is the process by which an extracellular signaling molecule activates a membrane receptor that in turn alters intracellular molecules creating a response. Transmembrane receptors span the cell membrane with part of the receptor outside and part inside the cell. The chemical signal binds to the outer portion of the receptor changing its shape and conveying another signal inside the cell. Some chemical messengers such as testosterone can pass through the cell membrane and bind directly to receptors in the cytoplasm or nucleus. Sometimes there is a cascade of signals within the cell. With each step of the cascade... read more
Tel: 6316197922
Signal transduction is the process by which an extracellular signaling molecule activates a membrane receptor that in turn alters intracellular molecules creating a response. Transmembrane receptors span the cell membrane with part of the receptor outside and part inside the cell. The chemical signal binds to the outer portion of the receptor changing its shape and conveying another signal inside the cell. Some chemical messengers such as testosterone can pass through the cell membrane and bind directly to receptors in the cytoplasm or nucleus. Sometimes there is a cascade of signals within the cell. With each step of the cascade... read more
45-1 Ramsey Road, Shirley, New York 1196, Shirley
Tel: 6316197922
Immunology is a broad branch of biomedical science that covers the study of all aspects of the immune system in all organisms. It deals with the physiological functioning of the immune system in states of both health and disease; malfunctions of the immune system in immunological disorders (autoimmune diseases hypersensitivities immune deficiency transplant rejection); the physical chemical and physiological characteristics of the components of the immune system in vitro in situ and in vivo. Immunology has applications in several disciplines of science and as such is further divided.... read more
Tel: 6316197922
Immunology is a broad branch of biomedical science that covers the study of all aspects of the immune system in all organisms. It deals with the physiological functioning of the immune system in states of both health and disease; malfunctions of the immune system in immunological disorders (autoimmune diseases hypersensitivities immune deficiency transplant rejection); the physical chemical and physiological characteristics of the components of the immune system in vitro in situ and in vivo. Immunology has applications in several disciplines of science and as such is further divided.... read more
45-1 Ramsey Road, Shirley, NY 11967, USA, Shirley
Tel: 6316197922
The Cardiovascular Biology Division is made up of over thirty faculty members from basic science and clinical departments with the goal of training students for careers as independent investigators studying the molecular and cellular aspects of cardiovascular physiology and disease.... read more
Tel: 6316197922
The Cardiovascular Biology Division is made up of over thirty faculty members from basic science and clinical departments with the goal of training students for careers as independent investigators studying the molecular and cellular aspects of cardiovascular physiology and disease.... read more
45-1 Ramsey Road, Shirley, New York 11967, USA, Shirley
Tel: 6316197922
Cancer is fundamentally a disease of failure of regulation of tissue growth. In order for a normal cell to transform into a cancer cell the genes which regulate cell growth and differentiation must be altered. The affected genes are divided into two broad categories. Oncogenes are genes which promote cell growth and reproduction. Tumor suppressor genes are genes which inhibit cell division and survival. Malignant transformation can occur through the formation of novel oncogenes the inappropriate over-expression of normal oncogenes or by the under-expression or disabling of tumor suppressor genes. Typically changes in many genes are required to transform a... read more
Tel: 6316197922
Cancer is fundamentally a disease of failure of regulation of tissue growth. In order for a normal cell to transform into a cancer cell the genes which regulate cell growth and differentiation must be altered. The affected genes are divided into two broad categories. Oncogenes are genes which promote cell growth and reproduction. Tumor suppressor genes are genes which inhibit cell division and survival. Malignant transformation can occur through the formation of novel oncogenes the inappropriate over-expression of normal oncogenes or by the under-expression or disabling of tumor suppressor genes. Typically changes in many genes are required to transform a... read more
376 Canterbury Rd, Surrey Hills
Tel: 03 9888 5899
Dartnells Pharmacy is a compounding-only pharmacy that specialises in providing tailor-made medicine to suit a patient's specific needs.This encompasses bio-identical hormone replacement dermatology veterinary pediatrics nutritional and vitamin specific formula and unique OTC formulations from its century old history.... read more
Tel: 03 9888 5899
Dartnells Pharmacy is a compounding-only pharmacy that specialises in providing tailor-made medicine to suit a patient's specific needs.This encompasses bio-identical hormone replacement dermatology veterinary pediatrics nutritional and vitamin specific formula and unique OTC formulations from its century old history.... read more
10038 Bishops Gate Blvd, Pineville
Tel: 1-800-282-2318
Our team is led by Roland Thomas who has been working with pharmacy entrepreneurs and managers for decades. Roland has held a General Contractor’s license for over seven years that brings an additional benefit. We work closely with your local contractor and/or architect and receive bids from qualified casework/fixture suppliers that meet the specifications.... read more
Tel: 1-800-282-2318
Our team is led by Roland Thomas who has been working with pharmacy entrepreneurs and managers for decades. Roland has held a General Contractor’s license for over seven years that brings an additional benefit. We work closely with your local contractor and/or architect and receive bids from qualified casework/fixture suppliers that meet the specifications.... read more
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